CK1 epsilon (R178C Mutant) Proteins

CK1 epsilon (R178C Mutant) Human recombinant proteins are validated for use in the following applications: Kinase Assay. Available Product Grades: RUO. Browse 1 protein. Not finding the exact protein, grade or size needed?... CK1 epsilon (R178C Mutant) Human recombinant proteins are validated for use in the following applications: Kinase Assay. Available Product Grades: RUO. Browse 1 protein. Not finding the exact protein, grade or size needed? Contact us... CK1 epsilon (R178C Mutant) Human recombinant proteins are validated for use in the following applications: Kinase Assay. Available Product Grades: RUO. Browse 1 protein. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.... CK1 epsilon (R178C Mutant) Human recombinant proteins are validated for use in the following applications: Kinase Assay. Available Product Grades: RUO. Browse 1 protein. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.

Protein Information

CSNK1E serine/threonine kinase is a member of the CK1 family which plays an important role in diverse cell processes, including DNA replication and repair. CSNK1E is a regulator of Yes-associated protein (YAP) transcription coactivator, which is a key regulator of organ size and a candidate human oncogene. CSNK1E is activated by CCK2R and then phosphorylates PKD2 at Ser244. Phosphorylation of PKD2 leads to its nuclear accumulation and efficient phosphorylation of nuclear PKD2 substrates in human gastric cancer cells. CSNK1E can phosphorylate topoisomerase (topo) II alpha at serine-1106 and this regulates the enzyme activity and sensitivity to topo II-targeted drugs.

Synonyms

CK1

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Invitrogen

Human CSNK1E (CK1 epsilon) [R178C], GST Tag Recombinant Protein

Invitrogen

Human CSNK1E (CK1 epsilon) [R178C], GST Tag Recombinant Protein

Species

Human

Expression System

Insect cells

Product Grade

Research Use Only

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Cat # A33498

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CK1 epsilon (R178C Mutant) Proteins

Protein Information

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